Kalkulator TPE
Formulasi & Sumber Medis
Formulasi Matematika TPE Anak
1. Total Blood Volume (TBV):
$$\text{TBV (mL)} = \text{Berat Badan (kg)} \times \text{EBV (mL/kg)}$$ (Nilai Standar EBV Anak: 70 cc/kgBB)2. Extracorporeal Volume (ECV) Ratio:
$$\text{ECV (\%)} = \left(\frac{\text{Volume Bowl}}{\text{TBV}}\right) \times 100\%$$ (Batas aman toleransi priming alat tanpa PRC pada anak: < 10–15% dari TBV)3. Estimated Plasma Volume (EPV):
- Metode Kaplan / Nadler (Sesuai BB/Luas Permukaan): $$\text{EPV} = (1 - \text{Hct}) \times (864 + 47{,}2 \times \text{BB})$$
- Metode Standar TBV: $$\text{EPV} = \text{TBV} \times \left(1 - \frac{\text{Hct}}{100}\right)$$
4. Total Plasma Volume Target (TPV):
$$\text{TPV} = 1{,}5 \times \text{EPV}$$Sitasi Medis & Pedoman Resmi
1. ASFA Guidelines (2023 / 9th Edition):
Connelly-Smith L, et al. Guidelines on the Use of Therapeutic Apheresis in Clinical Practice – Evidence-Based Approach from the Writing Committee of the American Society for Apheresis: The Ninth Special Issue. J Clin Apher. 2023.
2. Kaplan AA. (1990):
Kaplan AA. A simple technique for estimating plasma volume in patients undergoing plasma exchange. Trans Am Soc Artif Intern Organs. 1990;36(3):M165-M167.
3. Pediatric Critical Care Medicine (PCCM) Guidelines:
Fortenberry JD, et al. Therapeutic Plasma Exchange in Pediatric Critical Illness. Pediatr Crit Care Med. 2010.
Connelly-Smith L, et al. Guidelines on the Use of Therapeutic Apheresis in Clinical Practice – Evidence-Based Approach from the Writing Committee of the American Society for Apheresis: The Ninth Special Issue. J Clin Apher. 2023.
2. Kaplan AA. (1990):
Kaplan AA. A simple technique for estimating plasma volume in patients undergoing plasma exchange. Trans Am Soc Artif Intern Organs. 1990;36(3):M165-M167.
3. Pediatric Critical Care Medicine (PCCM) Guidelines:
Fortenberry JD, et al. Therapeutic Plasma Exchange in Pediatric Critical Illness. Pediatr Crit Care Med. 2010.
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